Sister cities of Winston-Salem, North Carolina

Winston-Salem is a city in the U.S. state of North Carolina, with a 2010 population of 229,617. Winston-Salem is the county seat and largest city of Forsyth County and the fifth largest city in the state.

Winston-Salem is the second largest municipality in the Piedmont Triad region and is home to the tallest office building in the region, 100 North Main Street, formerly the Wachovia Building and now known locally as the Wells Fargo Center. Winston-Salem is called the "Twin City" for its dual heritage and "City of the Arts and Innovation" for its dedication to fine arts and theater and technological research. "Camel City" is a reference to the city's historic involvement in the tobacco industry related to locally based R. J. Reynolds Tobacco Company's popular Camel cigarettes. Winston-Salem is also known for its traditional furniture company. Many locals refer to the city as "Winston" in informal speech. "The Dash" is referenced from the hyphen between Winston and Salem and was popularized by the nickname of the local minor league baseball team, the Winston-Salem Dash.

In 2013, the U.S. Office of Management and Budget reconfigured the Winston-Salem MSA by adding the Thomasville–Lexington micropolitan statistical area. The official 2010 Census population for the redefined Winston-Salem, North Carolina MSA was 640,595; according to 2012 Census estimates, the population was 647,697. The Greensboro – Winston-Salem – High Point combined statistical area (CSA), popularly referred to as the Piedmont Triad, had a population of 1,611,243 according to 2012 Census estimates.